Amlodipine, like chlorthalidone, has a substantial half-life (40-60 hrs) and consequently more tolerant of missed doses. It has a significant evidence base demonstrating reduction of CVD events, and thus can be prescribed as an initial or add-on agent. It is effective regardless of age, race, or renal function. In patients with kidney dysfunction, it should be combined with an Angiotensin-converting-enzyme inhibitors (ACEi) or Angiotensin II Receptor Blockers (ARB).
Everyone, regardless of their cardiovascular health, can gain benefits by improving their nutrition and healthy eating behaviors and by increasing physical activity. Studies show that adults who follow national guidelines for a healthy diet and physical activity have fewer cardiovascular problems and lower death rates than those who do not.
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The Ohio Cardiovascular Health Collaborative is funded by the Ohio Department of Medicaid and administered by the Ohio Colleges of Medicine Government Resource Center. The views expressed in this [presentation, publication, report] are solely those of the authors and do not represent the views of the state of Ohio or federal Medicaid programs.